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The Positives and Negatives of NPR: A Unifying Model for Salicylic Acid Signaling in Plants
- Innes, Roger
- Cell 2018 v.173 no.6 pp. 1314-1315
- gene expression, models, proteins, salicylic acid, transcription (genetics)
- Salicylic acid (SA) is a potent inducer of defense gene expression in plants, but how SA activates transcription has been controversial. In this issue of Cell, Ding et al. show that the SA-binding proteins NPR3 and NPR4 function as transcriptional co-repressors, with this activity being blocked by SA.