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Epigenetic Control of Autophagy: Nuclear Events Gain More Attention
- Baek, Sung Hee, Kim, Keun Il
- Molecular cell 2017 v.65 no.5 pp. 781-785
- autophagy, cytoplasm, epigenetics
- Autophagy is an evolutionarily conserved catabolic process. Although the components of autophagy in cytoplasm have been well-studied, the molecular basis for the epigenetic regulation of autophagy is poorly understood. It is becoming more important to propose a “whole-cell view” of autophagy embracing both cytoplasmic and nuclear events. Thus, it is great timing to summarize current status and discuss future direction.