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Advancement in the treatment of haemophilia

Author:
Bhardwaj, Rahul, Rath, Goutam, Goyal, Amit K.
Source:
International journal of biological macromolecules 2018 v.118 pp. 289-295
ISSN:
0141-8130
Subject:
disease control, gene therapy, hemophilia, hemorrhage, patients, pharmacokinetics
Abstract:
Poor understanding of the pathophysiological mechanisms involved in Haemophilia is a major obstacle in accessing effective haemophilia disease management. Haemophilia is a life-frightening bleeding problem in which there are repeated bleeding episodes. Various approaches have been used, involves clotting factor replacement therapy for effective bleeding control in Haemophilia. Current advancements in the management of patients with haemophilia include altered pharmacokinetics clotting factor concentrates for better prophylaxis and management of haemophilia. This review sums up the prophylactic treatment, novel production techniques, other treatment techniques and the present position of gene therapy in the treatment of haemophilia.
Agid:
6129728