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Pd-catalyzed selective decarboxylation/C–H activation coupling of aryl acid with thiazole and oxazole directed by 1,2,3-triazole

Author:
Ma, Xinyuan, Liu, Yaowen, Xie, Kai, Jiang, Yubo
Source:
Tetrahedron letters 2018
ISSN:
0040-4039
Subject:
catalytic activity, chemical reactions, moieties, oxazoles, palladium, thiazoles, triazoles
Abstract:
An efficient palladium-catalyzed selective decarboxylation/C–H activation coupling of aryl acid with thiazole and oxazole under the assistance of 1,2,3-triazole ring were developed. This work provides an effective access to build functionalized 1,2,3-triazoles bearing thiazole and oxazole moieties. This method has good substrate compatibility to compose a series of selective heterocyclic compounds in moderate to good yields.
Agid:
6130923