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Exposure to sublethal concentrations of tributyltin reduced survival, growth, and 20-hydroxyecdysone levels in a marine mysid

Author:
Kim, Bo-Mi, Saravanan, Manoharan, Lee, Do-Hee, Kang, Jung-Hoon, Kim, Moonkoo, Jung, Jee-Hyun, Rhee, Jae-Sung
Source:
Marine environmental research 2018 v.140 pp. 96-103
ISSN:
0141-1136
Subject:
Malacostraca, acute toxicity, adults, antifouling agents, aquatic organisms, bioaccumulation, boats, ecdysterone, females, juveniles, mechanism of action, molting, mortality, neonates, paints, sublethal effects, toxicity testing, tributyltin
Abstract:
Tributyltin (TBT) is as an antifouling organotin compound used in boat paints. Although organotin-based antifouling agents have been banned on a global scale, the mode of action of TBT has been studied in numerous aquatic species because of its toxicity, persistence, bioaccumulation potential, and endocrine-disrupting characteristics. In this study, we conducted 96-h acute toxicity tests wherein we exposed juvenile and adult marine mysids to waterborne TBT. Over 4 weeks of exposure, mortality was dose-dependently increased in juveniles and adult mysids. To test sublethal effects of TBT on juvenile development, newborn juvenile mysids were exposed to 1, 5, or 10 ng L−1 TBT for 4 weeks. Subsequently, we measured morphological growth parameters and quantified the hormone ecdysterone (20-hydroxyecdysone: 20E), which controls molting in mysids. The lengths of the whole body, antennal scale, exopod, endopod, and telson were significantly smaller in the 5 and/or 10 ng L−1 TBT-exposed juvenile mysids than in control and DMSO-exposed groups. Levels of 20E were significantly lower at 5 and 10 ng L−1 TBT exposures. Additionally, the number of newly hatched juveniles was significantly lower from females previously exposed to 10 ng L−1 TBT. Our results indicate sublethal concentrations of TBT have inhibitory effects on the survival, growth, and production of juveniles. The lower 20E levels could be strongly associated with TBT-triggered inhibition.
Agid:
6137477