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Self-Digestion for Lifespan Extension: Enhanced Autophagy Delays Aging

Author:
Arensman, Michael D., Eng, Christina H.
Source:
Molecular cell 2018 v.71 no.4 pp. 485-486
ISSN:
1097-2765
Subject:
autophagy, longevity, mammals, mutation
Abstract:
By systemically boosting autophagy with a knockin mutation that prevents binding of beclin 1 to BCL2, Fernández et al. (2018) demonstrate that enhanced autophagy prolongs lifespan in mammals.
Agid:
6157721