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Gall bladder mucoceles in Border terriers

Author:
Allerton, F., Swinbourne, F., Barker, L., Black, V., Kathrani, A., Tivers, M., Henriques, T., Kisielewicz, C., Dunning, M., Kent, A.
Source:
Journal of veterinary internal medicine 2018 v.32 no.5 pp. 1618-1628
ISSN:
0891-6640
Subject:
Cocker Spaniel, Shetland Sheepdog, case-control studies, confidence interval, dog diseases, dogs, gall bladder, hospitals, medical records, odds ratio, risk factors, signs and symptoms (animals and humans), terriers, ultrasonography, United Kingdom
Abstract:
BACKGROUND: Gall bladder mucoceles (GBM) are a leading cause of biliary disease in dogs with several breeds, including the Shetland Sheepdog, American Cocker Spaniel, Chihuahua, Pomeranian, and Miniature Schnauzer apparently predisposed. OBJECTIVE: To determine risk factors, clinical features, and response to treatment of GBM in Border terriers (BT). ANIMALS: Medical records of 99 dogs (including 51 BT) with an ultrasonographic (±histopathologic) diagnosis of GBM from three referral centers in the United Kingdom were collected. A control group of 87 similar‐aged BT with no ultrasonographic evidence of gall bladder disease was selected for comparison. METHOD: Retrospective case‐control study. Odds ratios were calculated to establish breed predisposition. Signalment, presence of endocrine disease, clinicopathologic results, and outcome were compared between the BT, other breeds, and control BTs. RESULTS: The odds of identifying a GBM in a BT in this hospital population was 85 times that of all other breeds (95% confidence interval 56.9‐126.8). BT had similar clinical signs and clinicopathologic changes to other breeds with GBM. There was no evidence that endocrinopathies were associated with GBM in BT. CLINICAL SIGNIFICANCE: A robust breed predisposition to GBM is established for the BT.
Agid:
6163960