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Effects of dietary selenium on host response to necrotic enteritis in young broilers

Author:
Xu, Shouzhen, Lee, Sung-Hyen, Lillehoj, Hyun S., Hong, Yeong Ho, Bravo, David
Source:
Research in veterinary science 2015 v.98 pp. 66
ISSN:
0034-5288
Subject:
Clostridium perfringens, Eimeria maxima, antibodies, body weight, broiler chickens, coccidiosis, dietary supplements, digestive system, excretion, feces, inducible nitric oxide synthase, interleukin-1beta, interleukin-6, interleukin-8, lesions (animal), messenger RNA, necrotic enteritis, oocysts, selenium, spleen
Abstract:
The effects of dietary supplementation of young broiler chickens with an organic selenium (Se) formulation, B-Traxim Se, on experimental necrotic enteritis (NE) were studied. Chickens treated with three Se doses (0.25, 0.50, 1.00 mg/kg) from hatch were orally challenged with Eimeria maxima at 14 days of age followed by Clostridium perfringens to induce NE. Chickens fed with 0.50 mg/kg Se showed significantly increased body weights and antibody levels against NetB, and significantly reduced gut lesions compared with non-supplemented chickens. However, there were no significant differences in Eimeria oocyst shedding between the Se-treated and non-supplemented groups. Levels of IL-1β, IL-6, IL-8, iNOS, LITAF, TNFSF15, AvBD6, AvBD8, and AvBD13 transcripts were increased in the gut and spleen of at least one of the three Se-treated groups compared with the non-treated group. These results suggest that dietary supplementation of young broilers with Se might be beneficial to reduce the negative consequence of NE.
Agid:
61649
Handle:
10113/61649