Jump to Main Content
Metabolic glycan labeling-assisted discovery of cell-surface markers for primary neural stem and progenitor cells
- BaiThese authors contributed equally to this work., Qing-Ran, Dong, Lu, Hao, Yi, Chen, Xing, Shen, Qin
- Chemical communications 2018 v.54 no.43 pp. 5486-5489
- chemical compounds, chemical reactions, coculture, moieties, neural stem cells
- A chemical approach was developed for identifying cell-surface markers for primary neural stem cells (NSCs). Using an in vitro coculture system of primary NSCs combined with metabolic labeling of sialoglycans with bioorthogonal functional groups, we selectively enriched and identified a list of cell-surface sialoglycoproteins that were more abundantly expressed in neural stem and progenitor cells.