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Platinum(iv) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance
- ChenThese authors contributed equally to this work., Qiling, Yang, Yuanyuan, Lin, Xun, Ma, Wen, Chen, Gui, Li, Wenliang, Wang, Xuefeng, Yu, Zhiqiang
- Chemical communications 2018 v.54 no.42 pp. 5369-5372
- chemical reactions, cisplatin, lipids, nanoparticles, platinum
- Platinum(iv) prodrugs of clinically used cisplatin and oxaliplatin with two axial long lipid chains were developed for nanoparticle delivery to combat cisplatin resistance.