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BINOL-phosphoric acids-catalyzed furylogous pinacol rearrangement of 1-[5-(hydroxy-diaryl-methyl)-furan-2-yl]-cyclobutanols into spiro cyclopentanones

Author:
Fei, Chengcheng, Liu, Jianchao, Peng, Hui, Jiang, Dingxin, Yin, Biaolin
Source:
Tetrahedron 2018
ISSN:
0040-4020
Subject:
catalysts, chemical reactions, chemical structure, enantioselectivity, organic compounds, phosphoric acid
Abstract:
A BINOL-phosphoric acid-catalyzed furylogous Pinacol rearrangement is developed. This reaction produces spiro cyclopentanone in good yields under mild conditions. The enantioselective version of this reaction is also investigated using chiral phosphoric acid (CPA) as the catalyst.
Agid:
6176266