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BINOL-phosphoric acids-catalyzed furylogous pinacol rearrangement of 1-[5-(hydroxy-diaryl-methyl)-furan-2-yl]-cyclobutanols into spiro cyclopentanones
- Fei, Chengcheng, Liu, Jianchao, Peng, Hui, Jiang, Dingxin, Yin, Biaolin
- Tetrahedron 2018
- catalysts, chemical reactions, chemical structure, enantioselectivity, organic compounds, phosphoric acid
- A BINOL-phosphoric acid-catalyzed furylogous Pinacol rearrangement is developed. This reaction produces spiro cyclopentanone in good yields under mild conditions. The enantioselective version of this reaction is also investigated using chiral phosphoric acid (CPA) as the catalyst.