PubAg

Main content area

A highly fluorescent turn-on probe in the near-infrared region for albumin quantification in serum matrix

Author:
Chakraborty, Goutam, Ray, Alok K., Singh, Prabhat K., Pal, Haridas
Source:
Chemical communications 2018 v.54 no.60 pp. 8383-8386
ISSN:
1364-548X
Subject:
blood serum, chemical compounds, chemical reactions, fluorescence, fluorescent dyes, serum albumin
Abstract:
Developing sensitive and selective near-infrared fluorescent bio-probes for serum albumin detection is an ambitious and highly rewarding task. Herein, we report a styryl based fluorophore for serum albumin detection, which displays an exceptional turn-on emission enhancement of ∼500 fold, the highest reported so far in the near-infrared region, and more importantly enables quantification of albumin in the complex serum matrix.
Agid:
6177932