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Entering the Pocket: Crystal Structure of a Prostaglandin D2 Receptor
- Baidya, Mithu, Kumari, Punita, Shukla, Arun K.
- Molecular cell 2018 v.72 no.1 pp. 3-6
- G-protein coupled receptors, crystal structure, ligands, prostaglandins, therapeutics
- In this issue of Molecular Cell, crystal structures of a prostaglandin D2 receptor determined by Wang et al. (2018) reveal novel insights into differential ligand recognition among the members of lipid-binding GPCRs, and provide a structural framework for the identification of novel therapeutics in inflammatory disorders.