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Amberlite-15 promoted an unprecedented aza Michael rearrangement for one pot synthesis of dihydroquinazolinone compounds

Author:
Murthy, V. Narayana, Nikumbh, Satish P., Tadiparthi, Krishnaji, Madhubabu, M. V., Jammula, Subba Rao, Rao, L. Vaikunta, Raghunadh, Akula
Source:
RSC advances 2018 v.8 no.40 pp. 22331-22334
ISSN:
2046-2069
Subject:
aldehydes, amines, catalysts, reaction mechanisms
Abstract:
A new one pot multicomponent annulation strategy for the synthesis of various dihydroquinazolinone compounds has been developed using Amberlite-15 as a catalyst, giving good to moderate yields. In this reaction the substrate scope for amines and aldehydes was also investigated. The reaction has been checked on a large scale and the possible reaction mechanism has also been proposed.
Agid:
6185928