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Acute effect of fine and coarse particular matter on cardiovascular visits in Ningbo, China

Pei-wen Zheng, Peng Shen, Zhen-hua Ye, Zhen-yu Zhang, Peng-fei Chai, Die Li, Ming-juan Jin, Meng-Ling Tang, Huai-chu Lu, Hong-bo Lin, Jian-bing Wang, Kun Chen
Environmental science and pollution research international 2018 v.25 no.33 pp. 33548-33555
acute effects, adverse effects, cold, cold season, elderly, epidemiological studies, hospitals, models, particulates, China
Although a growing number of epidemiological studies have been conducted on size-specific health effects of particulate matter in China, results remain inconsistent. In this study, we investigated acute effect of fine and coarse particular matter on cardiovascular hospital visits in Ningbo, China. We used generalized additive models to examine short-term effects of PM₂.₅ and PM₁₀–₂.₅ on cardiovascular hospital visits by adjustment for temporal, seasonal, and meteorological effects. Subgroup analyses were conducted by age, sex, and season. We also examined the stability of their effects in multi-pollutant models. We found that PM₂.₅ were associated with cardiovascular hospital visits (RR = 1.006; 95% CI 1.000, 1.011) and results remained similar after adjustment for PM₁₀–₂.₅ (RR = 1.005; 95% CI 0.998, 1.013). There was a borderline association between PM₁₀–₂.₅ and cardiovascular hospital visits (RR = 1.007; 95% CI 0.997, 1.016), which disappeared after controlling for PM₂.₅ (RR = 1.000; 95% CI 0.988, 1.013). The associations appeared to be stronger in the cold season and among the elderly (≥ 75 years). The findings of this study suggested significant adverse effects of PM₂.₅, but no independent effects of PM₁₀–₂.₅ on cardiovascular hospital visits. Additional studies are needed to confirm these findings.