PubAg

Main content area

Comparison of the effect of oxygen supplementation using flow-by or a face mask on the partial pressure of arterial oxygen in sedated dogs

Author:
Wong, AM, Uquillas, E, Hall, E, Dart, CM, Dart, AJ
Source:
New Zealand veterinary journal 2019 v.67 no.1 pp. 36-39
ISSN:
1176-0710
Subject:
air, blood, blood gases, breathing, cross-over studies, dogs, face masks, medetomidine, methadone, nose, oxygen, patients, temperature
Abstract:
To compare the effect of oxygen supplementation using flow-by or a face mask on the partial pressure of arterial oxygen (PaO₂) in sedated dogs. Twenty healthy dogs weighing >15 kg, of mixed sex and breed, were enrolled in a randomised cross-over study. Each dog was sedated with I/M 0.015 mg/kg medetomidine and 0.5 mg/kg methadone. Twenty minutes later dogs were exposed to two 5-minute treatment periods of oxygen supplementation separated by a 15-minute washout period during which dogs were allowed to breathe room air. During the treatment periods, oxygen was delivered at a flow rate of 3 L/minute either through a face mask (face mask oxygenation), or via a tube held 2 cm from the dog’s nares (flow-by oxygenation). The order in which the treatments were administered was randomised. Arterial blood was collected for blood gas analysis and rectal temperature measured at four times: prior to commencing treatments, after each treatment, and at the end of the 15 minutes washout period between treatments. The mean PaO₂ in arterial samples taken from the dogs after face mask oxygen supplementation was 371.3 (SE 13.74) mmHg which was higher than in samples taken after they received flow-by oxygen supplementation (182.2 (SE 6.741) mmHg; p<0.001). The mean PaO₂ in samples taken after receiving either form of oxygen supplementation was higher than in samples taken after the dogs had been breathing room air (82.43 (SE 2.143) mmHg; p<0.001). There was no association between sex, age, weight or breed of dogs and blood gas parameters or rectal temperature (p>0.05). Oxygen supplementation delivered using a face mask was more effective at increasing PaO₂ than flow-by oxygen supplementation. Flow-by oxygen supplementation at a distance of 2 cm from the nose may be a suitable alternative when the use of a face mask is not tolerated by the patient.
Agid:
6220522