PubAg

Main content area

Enhancing Therapy: It’s about Time

Author:
Brown, Myles
Source:
Cell 2018 v.174 no.4 pp. 771-772
ISSN:
0092-8674
Subject:
diet, diurnal variation, drugs, genes, lipid metabolism, obesity, therapeutics
Abstract:
How diet and obesity impact diurnal changes in physiology remains unclear. In this issue of Cell, Guan et al. report that diet-induced obesity modulates the activity of circadian gene enhancers including those regulating lipid metabolism and show that the efficacy of lipid-lowering drugs depends on the time of administration.
Agid:
6233047