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Revitalizing Aging Skin through Diet
- Millar, Sarah E.
- Cell 2018 v.175 no.6 pp. 1461-1463
- dermis, diet, fibroblasts
- Mechanisms underlying aging of the skin dermis are poorly understood. Now, two studies (Marsh et al., 2018; Salzer et al., 2018) describe complementary approaches to this question: Salzer et al. show that aging dermal fibroblasts lose defined identity in a diet-influenced fashion, and Marsh et al. reveal that fibroblast loss over time is compensated by membrane expansion rather than proliferation, resulting in decreased cellular density.