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Analysis of chemical constituents from Polygonatum cyrtonema after “Nine-Steam-Nine-Bask” processing
- Wang, Wen-Xiang, Zhang, Xian, Dabu, Xi-La-Tu, He, Juan, Yang, Sheng-Chao, Chen, Jun-Wen, Fan, Wei, Zhang, Guang-Hui, Ai, Hong-Lian, Hai, Mei-Rong
- Phytochemistry letters 2019 v.29 pp. 35-40
- Polygonatum cyrtonema, anti-inflammatory activity, chemical composition, glucose, inhibitory concentration 50, nitric oxide, spectral analysis
- Seven new compounds, known as polygonatine N1‒N7 (1‒7), and a known compound (8) were isolated from the ‘Nine-Steam-Nine-Bask’ processing product of Polygonatum cyrtonema Hua. The compounds’ structures were determined by spectroscopic analysis. All compounds were tested for dipeptidyl peptidase-4 (DPP-4) inhibition, glucose transport, and anti-inflammatory activities. Compound 8 suppressed NO production with an IC50 of 35.4 μM.