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L- asparaginase – A promising biocatalyst for industrial and clinical applications

Author:
Shakambari, Ganeshan, Ashokkumar, Balasubramaniem, Varalakshmi, Perumal
Source:
Biocatalysis and agricultural biotechnology 2019 v.17 pp. 213-224
ISSN:
1878-8181
Subject:
asparaginase, biocatalysts, food industry, therapeutics
Abstract:
L-asparaginase is a versatile enzyme with application in food and therapeutics and under constant quest for a reliable microbial source for commercial production. The review is an aid to comprehend the key milestones of L-asparaginase ever since its discovery, its potential sources, economical production strategies using cheaply available alternate substrates, its purification and downstream procedures reported so far, its characterization and the relevance of its application in food industry and therapeutics with an added clinical perspective.