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Concentrations and health risks of inorganic arsenic and methylmercury in shellfish from typical coastal cities in China: A simultaneous analytical method study

Li, Peng, Pan, Yushi, Fang, Yong, Du, Mengjia, Pei, Fei, Shen, Fei, Xu, Baocai, Hu, Qiuhui
Food chemistry 2019 v.278 pp. 587-592
adults, arsenic, children, cities, detection limit, health effects assessments, high performance liquid chromatography, mass spectrometry, methylmercury compounds, microwave treatment, neoplasms, seafood consumption, shellfish, China
Shellfish consumption is an important pathway for coastal residents exposure to inorganic arsenic (iAs) and methylmercury (MeHg). An integrated method had been developed for simultaneous determination of iAs and MeHg in shellfish with microwave-assisted extraction and high performance liquid chromatography-inductively coupled plasma mass spectrometry identification. The limits of detection were 0.0520, 0.1003 and 0.0015 mg/kg (dry weight) for AsIII, AsV and MeHg, respectively. The proposed method was applied to evaluate the contents and health risks of iAs and MeHg in shellfish from the typical coastal cities (Lianyungang and Yantai) in China. The concentrations of iAs and MeHg in fresh shellfish were 0.10–1.69 mg/kg and 0.46–6.38 μg/kg, respectively. The target hazard quotient and target cancer risk values of iAs were the highest for the children and adults in Lianyungang, and were respectively larger than 1 and 1 × 10−4, indicating both non-carcinogenic and carcinogenic risks of iAs exposure were significant in this area.