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Complete genome sequence of soil actinobacteria Streptomyces cavourensis TJ430

Wang, Peipei, Liu, Zhongqi, Huang, Yongchun
Journal of basic microbiology 2018 v.58 no.12 pp. 1083-1090
Streptomyces cavourensis, Streptomyces coelicolor, Streptomyces lividans, antibacterial properties, antibiotics, bacteria, chromosomes, genes, genomic islands, metabolism, mountain soils, nucleotide sequences, phylogeny, plasmids, ribosomal DNA, ribosomal RNA, stress tolerance, China
A new actinobacteria Streptomyces cavourensis TJ430 was isolated from the mountain soil collected from the southwest of China. In previous study, TJ430 showed striking bactericidal activities and strong ability of antibiotic production. Here, we report complete genome of this bacterium, consisting of 7.6 Mb linear chromosome and 0.2 Mb plasmids. It was predicted 6450 genes in chromosome and 225 genes in plasmids, as well as 12 gene islands in chromosome. Abundant genes have predicted functions in antibiotic metabolism and stress resistance. A whole‐genome comparison of S. cavourensis TJ430, S. coelicolor A3(2), and S. lividans 66 indicates that TJ430 has a relatively high degree of strain specificity. The 16S rRNA phylogenetic tree shows the high identities (99.79%) of TJ430 with S. cavourensis DSM40300. TJ430 is a new and rare Streptomyces species, and analysis of its genome helps us to better understand primary metabolism mechanism of this isolate, as well as the evolutionary biology.