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LEAP: constructing gene co-expression networks for single-cell RNA-sequencing data using pseudotime ordering

Author:
Specht, Alicia T., Li, Jun
Source:
Bioinformatics 2017 v.33 no.5 pp. 764-766
ISSN:
1460-2059
Subject:
algorithms, bioinformatics, computer software, genes, sequence analysis
Abstract:
Summary: To construct gene co-expression networks based on single-cell RNA-Sequencing data, we present an algorithm called LEAP, which utilizes the estimated pseudotime of the cells to find gene co-expression that involves time delay. Availability and Implementation: R package LEAP available on CRAN Contact: jun.li@nd.edu Supplementary information: Supplementary data are available at Bioinformatics online.
Agid:
6248440