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Synthesized sulfated and acetylated derivatives of polysaccharide extracted from Gracilariopsis lemaneiformis and their potential antioxidant and immunological activity

Author:
Wang, Xiaomei, Zhang, Zhongshan, Wu, Yi, Sun, Xue, Xu, Nianjun
Source:
International journal of biological macromolecules 2019 v.124 pp. 568-572
ISSN:
0141-8130
Subject:
B-lymphocytes, Fourier transform infrared spectroscopy, Gracilariopsis lemaneiformis, antioxidant activity, antioxidants, chemical analysis, food industry, pharmaceutical industry, polysaccharides
Abstract:
The sulfated and acetylated derivatives of the sulfated polysaccharide extracted from red algae Gracilariopsis lemaneiformis were synthesized, and their antioxidant and immunological activities were investigated. And then the relationship between the activity and chemical characteristics was characterized. The results of chemical analysis and FT-IR showed the modification of polysaccharide was successful. In addition, it was found that a certain derivative exhibited stronger antioxidant activity than the one unmodified in the same experiment. The sulfated and acetylated derivatives showed different activities on the T and B lymphocytes proliferation. They may be of potential value as a possible supplement in food and pharmaceutical industries.
Agid:
6253986