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Axial Suspension Plasma Spraying: An ultimate technique to tailor Ti6Al4V surface with HAp for orthopaedic applications

Author:
Hameed, Pearlin, Gopal, Vasanth, Bjorklund, Stefan, Ganvir, Ashish, Sen, Dwaipayan, Markocsan, Nicolaie, Manivasagam, Geetha
Source:
Colloids and surfaces 2019 v.173 pp. 806-815
ISSN:
0927-7765
Subject:
adhesion, biocompatibility, cell viability, coatings, colloids, contact angle, corrosion, fetal bovine serum, hardness, humans, hydroxyapatite, mesenchymal stromal cells, microstructure, orthopedics, porosity, spraying, umbilical cord
Abstract:
Dissolution of atmospheric plasma sprayed (APS) hydroxyapatite (HAp) coatings on Ti-6Al-4 V medical implants have always been a challenge to overcome in the field of biomedical industry. In the present work, an attempt has been made to develop a HAp coating using a novel thermal spray process called axial suspension plasma spraying (SPS), which leads to thin adherent coatings. Two HAp coatings fabricated by APS (P1 and P2) and four SPS HAp coatings (S1, S2, S3 and S4) produced with varying spraying parameters were characterized in terms of (1) microstructure, porosity, hardness, adhesion strength, contact angle and phase purity; (2) corrosion resistance in 10% Fetal bovine serum (FBS); (3) in-vitro cell adherence and cell viability using human umbilical cord blood-derived mesenchymal stem cells (hMSCs). Amongst different APS and SPS coatings, P1 and S3 exhibited superior properties. S3 coating developed using SPS exhibited 1.3 times higher adhesion strength when compared to APS coating (P1) and 9.5 times higher corrosion resistance than P1. In addition, both S3 and P1 exhibited comparatively higher biocompatibility as evidenced by the presence of more than 92% viable hMSCs.
Agid:
6255908