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Microfluidic synthesis and on-chip enrichment application of two-dimensional hollow sandwich-like mesoporous silica nanosheet with water ripple-like surface
- Hao, Nanjing, Nie, Yuan, Closson, Andrew B., Zhang, John X.J.
- Journal of colloid and interface science 2018
- adsorption, drugs, dyes, engineering, mass transfer, microfluidic technology, nanosheets, porous media, silica
- The merits of microfluidics bring new opportunities for engineering of nanomaterials with well controlled chemical, physical and biological properties for a variety of applications. Herein, using a two-run spiral-shaped microfluidic device, we first develop a facile and straightforward flow synthesis strategy to create two-dimensional mesoporous silica nanosheet (MSN). Such MSN exhibits typical hollow sandwich-like bilayer and unique water ripple-like wrinkle surface, which greatly increase the particulate accessibility for mass transfer. The enhanced on-chip enrichment performance of MSN is further confirmed toward different substrates (dye, protein, drug). These findings not only shed new light on microfluidics-enabled chemicals engineering, but also open up numerous new possibilities by microfluidics in adsorption, separation, and biomedical fields.