PubAg

Main content area

Fomitopsins I and J, 24-methyl-lanostane triterpenoids from fruiting bodies of the wood-rot basidiomycete Fomitopsis sp.

Author:
Isaka, Masahiko, Chinthanom, Panida, Suvannakad, Rapheephat, Thummarukcharoen, Tuksaporn, Feng, Tao, Liu, Ji-Kai
Source:
Phytochemistry letters 2019 v.29 pp. 178-181
ISSN:
1874-3900
Subject:
Bacillus cereus, Enterococcus faecium, Fomitopsis, Gram-positive bacteria, antibacterial properties, cytotoxicity, fruiting bodies, spectral analysis, triterpenoids
Abstract:
Two new 24-methyl-lanostane triterpenoids, fomitopsins I (1) and J (2), were isolated together with seven known compounds (3–9), from fruiting bodies of the basidiomycete Fomitopsis species. The structures were elucidated by spectroscopic analysis. Their antibacterial and cytotoxic activities were evaluated. One of the known compounds (6) exhibited antibacterial activity against Gram-positive bacteria, Bacillus cereus (MIC 6.25 μg/ml) and Enterococcus faecium (MIC 12.5 μg/ml).
Agid:
6258839