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Planting the Microbiome
- Spinler, Jennifer K., Karri, Vivekanudeep, Hirschi, Kendal D.
- Trends in microbiology 2019 v.27 no.2 pp. 90-93
- gene expression, immunity, intestinal microorganisms, lipids, microRNA, microbiome, nanoparticles, nutritional intervention, planting
- Plant-derived microRNAs stabilized by species-specific lipid nanoparticles mediate interkingdom communication through bacterial intermediates and impact consumer health. Ingested by distinct gut bacteria, these microRNA-containing particles alter bacterial gene expression to affect host immunity. This three-kingdom interplay provides compelling approaches for health-directed dietary interventions for consumers.