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Dietary supplementation with ferric tyrosine improves zootechnical performance and reduces caecal Campylobacter spp. load in broilers

Author:
Currie, D., Green, M., Dufailu, O. A., Matthaios, P., Soultanas, P., McCartney, E., Lester, H., Van Den Eede, L., Apajalahti, J., Mahdavi, J.
Source:
British poultry science 2018 v.59 no.6 pp. 646-653
ISSN:
1466-1799
Subject:
Campylobacter jejuni, Escherichia coli, Salmonella enterica, antimicrobial properties, birds, cecum, dietary supplements, enteropathogens, feed additives, feed conversion, food chain, males, mash, minimum inhibitory concentration, risk, simulation models, slaughter weight, tyrosine, weight gain
Abstract:
1. The objective of this study was to evaluate the effect of ferric tyrosine on the reduction of Campylobacter spp. and zootechnical performance in broilers exposed to Campylobacter spp. using a natural challenge model to simulate commercial conditions. Additionally, the minimum inhibitory concentrations (MICs) of ferric tyrosine against common enteropathogens were evaluated. 2. At the start of the trial, 840 healthy male 1-d-old birds (Ross 308) were randomly allocated to 6 replicate pens of 35 birds each and fed diets containing different concentrations of ferric tyrosine (0, 0.02, 0.05 and 0.2 g/kg) in mash form for 42 d. 3. Broilers fed diets containing ferric tyrosine showed significantly higher body weight at d 42 and weight gain compared to the control group. However, birds fed ferric tyrosine ate significantly more than the control birds so significant improvements in feed conversion rate were not observed. 4. Microbiological analyses of caecal samples collected on d 42 of the study showed, per gram of sample, 2–3 log₁₀ reduction in Campylobacter spp. and 1 log₁₀ reduction in Escherichia coli in the groups fed diets containing ferric tyrosine compared to the control. 5. The MICs of ferric tyrosine was >400 mg/l for C. jejuni and >200 mg/l for E. coli and Salmonella enterica, indicating that ferric tyrosine did not exert antimicrobial activity. 6. The results showed that birds fed ferric tyrosine grew faster and consumed more feed compared to the control group, indicating potential benefits of faster time to reach slaughter weight with no significant reduction on feed efficiency. Moreover, ferric tyrosine significantly reduced caecal Campylobacter spp. and E. coli indicating potential as a non-antibiotic feed additive to lower the risk of infections transmitted through the food chain.
Agid:
6268413