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A novel fluorescent turn-on probe for imaging biothiols based on SNAr substitution-skeletal rearrangement strategy

Author:
Ren, Aishan, Zhu, Dongjian, Zhong, Xing, Xiong, Yuhao, Duan, Zhenhua
Source:
Analytical methods 2019 v.11 no.3 pp. 262-267
ISSN:
1759-9679
Subject:
analytical methods, fluorescence, image analysis
Abstract:
A novel fluorescent turn-on probe 2 not only exhibited dramatic fluorescence enhancement by quinoline-to-quinolinone transformation, but also showed high sensitivity in the order Cys > GSH > Hcy. Importantly, 2 was successfully applied for imaging of biothiols in living cells.
Agid:
6269074