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Unlocking the catalytic potential of tris(3,4,5-trifluorophenyl)borane with microwave irradiation
- Carden, Jamie L., Gierlichs, Lukas J., Wass, Duncan F., Browne, Duncan L., Melen, Rebecca L.
- Chemical communications 2019 v.55 no.3 pp. 318-321
- aldehydes, alkenes, alkynes, catalytic activity, chemical reactions, imines, microwave radiation
- The catalytic activity of tris(3,4,5-trifluorophenyl)borane has been explored in the 1,2-hydroboration reactions of unsaturated substrates. Under conventional conditions, the borane was found to be active only in the hydroboration of aldehyde, ketone and imine substrates, with alkenes and alkynes not being reduced effectively. The use of microwave irradiation on the other hand has permitted alkenes and alkynes to be hydroborated in good yields.