Jump to Main Content
One step DNA amplification of mammalian cells in picoliter microwell arrays
- Liu, Wenwen, Li, Zhao, Liu, Yuanjie, Wei, Qingquan, Liu, Yong, Ren, Lufeng, Wang, Chenyu, Yu, Yude
- RSC advances 2019 v.9 no.5 pp. 2865-2869
- DNA, mammals, silica
- We developed a strategy for direct DNA amplification of single cells on a PEG-modified silica chip with 30 600 picoliter-sized microwells. HPV-positive cells in heterogeneous populations were successfully detected with high accuracy sensitivity as high as single copy.