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Optically Responsive, Smart Anti-Bacterial Coatings via the Photofluidization of Azobenzenes

Author:
Kehe, Gannon M., Mori, Dylan I., Schurr, Michael J., Nair, Devatha P.
Source:
ACS applied materials & interfaces 2019 v.11 no.2 pp. 1760-1765
ISSN:
1944-8252
Subject:
antibiotic resistance, antibiotics, bacteria, biofilm, coatings, drugs
Abstract:
Antibacterial strategies sans antibiotic drugs have recently garnered much interest as a mechanism by which to inhibit biofilm formation and growth on surfaces due to the rise of antibiotic-resistant bacteria. Based on the photofluidization of azobenzenes, we demonstrate for the first time the ability achieve up to a 4 log reduction in bacterial biofilms by opto-mechanically activating the disruption and dispersion of biofilms. This unique strategy with which to enable biofilm removal offers a novel paradigm with which to combat antibiotic resistance.
Agid:
6270638