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Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis

Author:
Auranwiwat, Chiramet, Wongsomboon, Puttandon, Thaima, Thanaphat, Rattanajak, Roonglawan, Kamchonwongpaisan, Sumalee, Willis, Anthony C., Laphookhieo, Surat, Pyne, Stephen G., Limtharakul, Thunwadee
Source:
Journal of natural products 2019 v.82 no.1 pp. 101-110
ISSN:
1520-6025
Subject:
Uvaria, X-ray diffraction, cyclohexenes, leaves, spectroscopy
Abstract:
The chemical study of leaf extracts from Uvaria cherrevensis resulted in the identification of 11 new polyoxygenated cyclohexenes, cherrevenols A–K (1–11), and a new seco-cyclohexene derivative, cherrevenol L (12). Nine known compounds (13–21) were also isolated. Three of the isolated compounds are chlorinated polyoxygenated cyclohexenes. The structures of these compounds were determined using spectroscopic methods and, in some cases (compounds 2, 6, 8, and 10), single-crystal X-ray crystallographic structural analysis or chemical correlation (compounds 6 and 7). Compounds 6 and 7 were both isolated as scalemic mixtures (ee 23–24%).
Agid:
6271409