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New depsidone and dichromone from the stems of Garcinia paucinervis with antiproliferative activity

Author:
Jia, CuiCui, Xue, JingJing, Li, XinYu, Li, DaHong, Li, ZhanLin, Hua, HuiMing
Source:
Natural medicines 2019 v.73 no.1 pp. 278-282
ISSN:
1340-3443
Subject:
Garcinia, cell lines, chromatography, neoplasm cells, spectral analysis, stems
Abstract:
A new depsidone, paucinervin Q (1), a new dichromone, paucinervin R (2), and a known compound, paucinervin B (3), were isolated from the stems of Garcinia paucinervis by various chromatographic methods. Their structures were determined by analysis of spectroscopic data. The isolates were evaluated for their antiproliferative activity against three cancer cell lines HL-60, PC-3 and CaCo-2. Compound 1 showed significant inhibitory activities.
Agid:
6275500