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Bioactive constituents obtained from the fruits of Citrus aurantium
- Zhang, Yi, Huang, Peijian, He, Wei, Sakah, Kaunda Joseph, Ruan, Jingya, Li, Zheng, Wang, Tao
- Natural medicines 2019 v.73 no.1 pp. 146-153
- Citrus aurantium, fruits, intestines, mice, nuclear magnetic resonance spectroscopy
- Three new compounds, citrusauranosides A (1), B (2), and C (3), along with 22 known compounds (4–25) were obtained from the 70% ethanol–water extract of the fruits of Citrus aurantium L.. Their structures were identified by spectroscopic methods. Among the known compounds, 14, 15, 17 and 23 were firstly obtained from Citrus genus, and the NMR data of 17 is reported here for the first time. Moreover, inhibitory effects of all compounds on motility of mouse isolated intestine tissue were determined. As a result, 1, 4–8, and 11 displayed significant inhibitory effects on contraction tension.