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Discovery of highly insecticidal synthetic spinosyn mimics – CAMD enabled de novo design simplifying a complex natural product

Author:
Sparks, Thomas C, Crouse, Gary D, Demeter, David A, Samaritoni, Geno, McLeod, Casandra L
Source:
Pest management science 2019 v.75 no.2 pp. 309-313
ISSN:
1526-498X
Subject:
computer simulation, insecticides, synthetic products
Abstract:
Simplifying complex natural products: Computer modeling‐based design leads to highly insecticidal, chemically simpler synthetic mimics of the spinosyn natural products that are active in the field. © 2018 Society of Chemical Industry
Agid:
6279351