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A pilot comparative study of recombinant protein and whole-virus inactivated vaccines against porcine circovirus type 2 in conventionally reared pigs
- Choi, Jong-Young, Lyoo, Kwang-Soo, Kim, Kiju, Do, Van Tan, Lee, Kyung-Won, Hahn, Tae-Wook
- Research in veterinary science 2019 v.123 pp. 192-194
- Porcine circovirus-2, coat proteins, immunity, inactivated vaccines, interferon-gamma, liveweight gain, neutralizing antibodies, rearing, recombinant proteins, swine, wasting syndrome, weight gain
- Porcine circovirus type 2 (PCV2) causes porcine circovirus-associated disease, which is characterized by systemic wasting syndrome, including respiratory problems worldwide. Most commercial PCV2 vaccines are derived from recombinant capsid protein or inactivated whole-virus. We compared average daily weight gain, interferon-γ, and neutralizing antibody levels of a recombinant protein vaccine and an inactivated whole-virus vaccine in a pilot study. Both PCV2 vaccines showed similar effect on immunity against PCV2 and a better average daily weight gain was found in both vaccinated groups compared to non-vaccinated animals.