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Ingestion bioaccessibility of indoor dust-bound PAHs: Inclusion of a sorption sink to simulate passive transfer across the small intestine

Author:
Gao, Peng, Liu, Dantong, Guo, Li, He, Chuan, Lin, Nan, Xing, Yanfeng, Yao, Changhao, Wu, Bing, Zheng, Zelin, Wang, Yue, Hang, Jian
Source:
The Science of the total environment 2019 v.659 pp. 1546-1554
ISSN:
0048-9697
Subject:
anthracenes, bioavailability, dust, ingestion, models, phenanthrenes, pollutants, risk assessment, silicone, small intestine, sorption, students, teachers
Abstract:
In this study, we investigated the levels of 12 priority polycyclic aromatic hydrocarbons (PAH12) pollutants, bioaccessible PAH12, and sorption sink for PAH12 by a silicone sheet of indoor dust samples, which were collected from teachers' offices (n = 17), students' offices (n = 17), laboratory (n = 11), and experimental center (n = 9), using an in vitro digestive model. In PAH12, bioaccessible PAH12, and sorption sink PAH12, benzo[b]fluoranthene (BbF), phenanthrenes (Phe), and fluoranthene (FLA) were labeled respectively the most significant PAHs (6.61 ± 4.42 μg/g, 0.16 ± 0.11 μg/g, and 0.08 ± 0.06 μg/g) after indoor dust ingestion, whereas the proportions of anthracene (Ant), benzo(g,h,i)perylene (BghiP), and BghiP (0.34 ± 0.17, 0.03 ± 0.03 and 0.01 ± 0.01 μg/g) were low. Based on benzo[a]pyrene- equivalent carcinogenic concentrations, the mean daily exposure of bioaccessible PAH12 and sorption sink for PAH12 by indoor dust ingestion was 4.07 × 10−3 ± 1.73 × 10−3 and 3.23 × 10−3 ± 1.36 × 10−3 μg/day in the experimental center; 4.01 × 10−3 ± 2.05 × 10−3 and 1.46 × 10−3 ± 6.72 × 10−4 μg/day in students' offices; 8.25 × 10−4 ± 2.33 × 10−4 and 5.15 × 10−4 ± 1.37 × 10−4 μg/day in laboratory; and 7.05 × 10−4 ± 4.12 × 10−5 and 2.82 × 10−4 ± 4.36 × 10−5 μg/day in teachers' offices, respectively. Our results indicated that the passive transfer fraction of PAH12 (44.07%–67.36% in this case) is therefore large and needs to be considered in exposure and risk assessments.
Agid:
6282364