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Black chokeberry (Aronia melanocarpa) polyphenols reveal different antioxidant, antimicrobial and neutrophil-modulating activities

Author:
Denev, Petko, Číž, Milan, Kratchanova, Maria, Blazheva, Denica
Source:
Food chemistry 2019 v.284 pp. 108-117
ISSN:
0308-8146
Subject:
Aronia melanocarpa, anthocyanins, anti-infective agents, antimicrobial properties, antioxidant activity, antioxidants, chemiluminescence, chlorogenic acid, epicatechin, fruits, humans, neutrophils, pathogens, proanthocyanidins, quercetin, rutin
Abstract:
The current study reports data on antioxidant, antimicrobial and neutrophil-modulating activities of different polyphenolic preparations from black chokeberry fruits: crude extract, purified extract standardized to 20% and 40% anthocyanins, and proanthocyanidins; as well as pure compounds (chlorogenic acid, cyanidin-3-O-galactoside, epicatechin, rutin and quercetin) present in black chokeberries. Minor phenolic components - quercetin and epicatechin showed the highest ORAC and TRAP antioxidant activity. Given the amount of individual phenolics in the fruits, proanthocyanidins are the major contributor to antioxidant activity of fresh black chokeberries. Studied polyphenols and preparations had no effect on the spontaneous chemiluminescence (CL) of human neutrophils and only mild effect on PMA-activated CL. Greater effects were observed on OZP-activated CL, being statistically significant (p < 0.05) for quercetin and rutin. The antimicrobial activity test against 10 pathogens showed that black chokeberry proanthocyanidins are the most potent antimicrobial agents in the fruit.
Agid:
6285189