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Sensing What’s Out There – Kinetoplastid Parasites
- Landfear, Scott M., Zilberstein, Dan
- Trends in parasitology 2019 v.35 no.4 pp. 274-277
- Leishmania, hosts, parasites, receptors, signal transduction, transporters
- Kinetoplastid parasites such as trypanosomes and Leishmania must adapt to their environments to survive within their hosts, yet they do not express many of the well established families of signal transduction receptors. Evidence suggests that other membrane proteins, including transporters and channels, play central roles in environmental sensing in these parasites.