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A ratiometric fluorescent probe of methionine sulfoxide reductase with an improved response rate and emission wavelength

Author:
Zhang, Liangwei, Peng, Shoujiao, Sun, Jinyu, Liu, Ruijuan, Liu, Shudi, Fang, Jianguo
Source:
Chemical communications 2019 v.55 no.10 pp. 1502-1505
ISSN:
1364-548X
Subject:
chemical communication, chemical reactions, enzyme activity, enzymes, fluorescence, fluorescent dyes, methionine, monitoring, wavelengths
Abstract:
A ratiometric fluorescent probe of methionine sulfoxide reductase, Msr-Ratio, was disclosed for monitoring the enzyme activity in vitro and in live cells. The probe displayed favorable properties such as a nearly 400-fold fluorescence change, fast response rate (<30 min), large Stokes shift (120 nm), and green emission (550 nm).
Agid:
6287770