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The Scourge of Antibiotic-resistant Infections in Cystic Fibrosis
- Price, Erin P., Sarovich, Derek S.
- Trends in microbiology 2019 v.27 no.4 pp. 289-291
- Burkholderia multivorans, antibiotic resistance, antibiotics, bacterial infections, cystic fibrosis, mortality, patients
- Bacterial infections are the primary cause of respiratory decline and mortality in cystic fibrosis (CF) patients. In a recent study, Diaz Caballero and colleagues  (PLoS Pathog. 2018;14:e1007453) catalogued the molecular adaptation of a decade-long Burkholderia multivorans infection in a Canadian CF patient, which evolved to become resistant towards multiple classes of antibiotics.