U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

Induction and transfer of resistance to poisoning by Amorimia (Mascagnia) septentrionalis in goats

Author:
Amélia L. L. Duarte, Rosane M. T. Medeiros, Fabrício K. L. Carvalho, Stephen T. Lee, Daniel Cook, James A. Pfister, Valéria M. M. Costa, Franklin Riet-Correa
Source:
Journal of applied toxicology 2014 v.34 no.2 pp. 220-223
ISSN:
1099-1263
Subject:
Malpighiaceae, biological resistance, goats, heart failure, poisoning, poisonous plants, sodium, toxicity, toxicology
Abstract:
Amorimia septentrionalis contains sodium monofluoroactetate (MFA) and can cause acute heart failure in ruminants when ingested in toxic doses. In this study, we demonstrate that resistance to poisoning by A. septentrionalis can be improved in goats by the repeated administration of non-toxic doses of A. septentrionalis.We also show that increased resistance to poisoning by A. septentrionalis can also be achieved by the transfaunation of ruminal content from goats previously conditioned to be resistant to naïve goats. These methods of improving resistance require further study, but appear to provide potential management solutions to mitigate toxicity problems from A. septentrionalis, and perhaps other plant species containing MFA.
Agid:
62954
Handle:
10113/62954