Main content area

Crown ether microfunctionalized carbon nanotubes for dispersive micro-solid-phase extraction of sudan dyes and their metabolites

Du, Li-Jing, Hu, Yu-Han, Wang, Qiu-Yan, Zhang, Qi-Dong, Chen, Yu-Bo, Peng, Li-Qing, Pan, Shu-Lei, Li, Qin, Cao, Jun
Food chemistry 2018 v.262 pp. 118-128
Sudan dyes, carbon nanotubes, detection limit, metabolites, solid phase extraction, sorbents, tandem mass spectrometry, ultra-performance liquid chromatography
In this study, dispersive micro solid phase extraction (DMSPE) combined with ultrahigh-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry method was established to extract and determine sudan dyes and their metabolites in real samples. The crown ether microfunctionalized multi-walled carbon nanotubes (MWCNTs) was applied as the sorbent in DMSPE procedure. Several experimental parameters that can effect the extraction performance of the DMSPE method were investigated separately by a univariate method. The validation data showed that the limits of detection were in the range of 0.084–13.13 μg/kg, the mean recoveries were ranged from 80.15 to 103.58% for six samples. Compared with other published methods, the proposed method was more effective, more time-saving and more eco-friendly. Finally, the developed method was successfully applied to enrich and detect sudan dyes and their metabolites in real samples.