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Chemiluminescence of Lucigenin/Riboflavin and Its Application for Selective and Sensitive Dopamine Detection

Author:
Lan, Yixiang, Yuan, Fan, Fereja, Tadesse Haile, Wang, Chao, Lou, Baohua, Li, Jianping, Xu, Guobao
Source:
Analytical chemistry 2018 v.91 no.3 pp. 2135-2139
ISSN:
1520-6882
Subject:
chemiluminescence, detection limit, dopamine, riboflavin
Abstract:
Lucigenin-riboflavin chemiluminescence is reported for the first time. Moreover, most dopamine chemiluminescence (CL) detection methods are based on the quenching of CL by dopamine. In contrast, we find that dopamine can significantly enhance lucigenin/riboflavin CL and establish a highly sensitive turn-on method for dopamine detection based on the enhancement of lucigenin/riboflavin CL. Under the optimal conditions, the CL intensity of the lucigenin/riboflavin system increased linearly with the concentration of dopamine in the range of 0.0056–55.56 μM, and the limit of detection is 1.87 nM.
Agid:
6300574