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Genomic characterization and comparative analysis of Leptospira kirschneri serogroup Grippotyphosa UC5/2011, a strain isolated after mare abortion: Implications for genital animal leptospirosis

Author:
Jaeger, Lauren H., Moreno, Luisa Z., Kremer, Frederico S., Dellagostin, Odir A., Moreno, Andrea M., Lilenbaum, Walter
Source:
Comparative immunology, microbiology, and infectious diseases 2019 v.64 pp. 7-9
ISSN:
0147-9571
Subject:
Leptospira kirschneri, abortion (animals), antibiotic resistance, evolution, genes, genomics, leptospirosis, mares, serotypes, virulence
Abstract:
The genome of a Brazilian strain of Leptospira kirschneri serogroup Grippotyphosa isolated from a mare post-abortion was sequenced and analyzed. High symmetrical identity and few structural differences were found when compared with a European strain of the same serogroup, L. kirschneri serovar Valbuzzi strain 200702274. Genes associated with virulence and antimicrobial resistance were found. Knowledge of the virulence evolution of Leptospira remains limited, especially in diseases of the reproductive sphere. We highlight the importance of virulence studies in the sphere of genital leptospirosis.
Agid:
6302963