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Phenolic glycosides from Lavandual angustifolia

Author:
Yadikar, Nigary, Bobakulov, Khayrulla, Aisa, H. A.
Source:
Journal of Asian natural products research 2018 v.20 no.11 pp. 1028-1037
ISSN:
1477-2213
Subject:
2,2-diphenyl-1-picrylhydrazyl, Lavandula angustifolia, antioxidant activity, dose response, essential oils, free radical scavengers, glycosides, melanin, melanoma, nuclear magnetic resonance spectroscopy, spectral analysis, wastes
Abstract:
Four new phenolic glycosides (1–4), together with 12 known ones (5–16), were isolated from the essential oil extraction waste of Lavandula angustifolia. Their structures were unequivocally determined by extensive spectroscopic analysis (1D and 2D NMR, HR-ESI-MS, UV, and optical rotation), chemical method, and comparison with data reported in the literature. The antioxidant activities of all compounds and new compounds’ influence on melanin content in B16 melanoma cells were examined, which indicated that compounds 1, 8, 13 had a certain degree of DPPH free radical scavenging activities, while only compound 2 could increase the melanin content with a dose-dependent manner.
Agid:
6305380