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A self-assembled peptide nucleic acid–microRNA nanocomplex for dual modulation of cancer-related microRNAs
- Wang, Xingxing, Xiao, Xiao, Zhang, Bingsen, Li, Jinbo, Zhang, Yan
- Chemical communications 2019 v.55 no.14 pp. 2106-2109
- chemical communication, chemical compounds, chemical reactions, microRNA, neoplasm cells, neoplasms
- Here, we report a new strategy for the construction of a peptide nucleic acid–microRNA nanocomplex with dual function to simultaneously suppress oncogenic microRNAs and upregulate tumor-suppressive microRNAs in target cancer cells.