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Precipitation as an Enabling Technology for the Intensification of Biopharmaceutical Manufacture

Author:
Martinez, Michael, Spitali, Mari, Norrant, Edith L., Bracewell, Daniel G.
Source:
Trends in biotechnology 2019 v.37 no.3 pp. 237-241
ISSN:
0167-7799
Subject:
antibodies, biopharmaceuticals, bioprocessing, cost effectiveness, manufacturing
Abstract:
Advances in precipitation have demonstrated the capability of purifying therapeutic proteins such as antibodies from biological sources in a scalable and cost-effective manner. We discuss the latest developments in the unit operation for downstream processing applications and provide a perspective on exploring precipitation for bioprocess intensification.
Agid:
6309322